CDS-plotcon: HBV - Hepatitis B Virus

Sequences used:

NC_003977, AB014366, AF046996, HBD50521, HBV131567, HBV131571, HBV131573, HBV131574, HBV18857, HBV18858, HBVADW4A, HBVAYWE, HBVAYWMCG, HHVBFFOU, HVHEPB.

ORF annotation:

NCBI reference sequence NC_003977.

Known features annotation:

C0 and J are short conserved ORFs from Chen A., Kao Y. F., Brown C. M., 2005, Translational of the first upstream ORF in the hepatitis B virus pregenomic RNA modulates translation at the core and polymerase initiation codons, Nucleic Acids Res., 33, 1169-1181. Epsilon is an encapsidation signal.
The S1, S2, C and X promoters (Pr-S1, Pr-S2, Pr-C, Pr-X), Enhancers I and II (Enh I, Enh II) and polyadenalation signal (poly-A) are from Moolla N., Kew M., Arbuthnot P., 2002, Regulatory elements of hepatitis B virus transcription, J. Viral Hepat., 9, 323-331.
The PRE regions (HSL-alpha, HSL-beta1) are from Smith G. J. 3rd, Donello J. E., Luck R., Steger G., Hope T. J., 1998, The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for function, Nucleic Acids Res., 26, 4818-4827.